Surgery Godfather

Chapter 2170: Chapter 1426: Surprise (3)

"Good!"

The next day, the cerebrospinal fluid was successfully extracted. Clara divided the sample into three parts: one for routine biochemical testing, one for ELISA testing of biphasic neurons and NeuroD concentrations, and one centrifuged for sediment to make cell smears. The cell smear was ready the next morning, Clara fixed, stained, and mounted the smear, and placed it under the microscope.

She saw a few scattered cells. Their morphology was very peculiar; they had large nuclei, little cytoplasm, and some tiny protrusions at the edges of the cell membrane. Clara stared at these cells for a long time and then stood up to find Manstein.

"Professor Manstein, come and take a look."

Manstein walked over and leaned towards the microscope. He adjusted the focus and found those cells in the field of view, remaining silent for a long time. "Did you do the biphasic neuron staining?"

"Yes, positive."

"What about NeuroD?"

"Also done, also positive."

Manstein straightened up, leaned against the lab bench, and looked at Clara. "This means that Clara’s cerebrospinal fluid contains biphasic neurons and NeuroD positive cells. These cells didn’t come from outside the blood-brain barrier; they shed into the cerebrospinal fluid from the spinal cord. This indicates primary cell activation and differentiation are occurring in his spinal cord."

"Should we inform Professor Yang?"

"Yes, but not now. Repeat it once more to ensure it’s not contamination. Take another sample of cerebrospinal fluid, centrifuge it again, stain it again. If we see the same cells, we’ll inform Professor Yang."

Clara repeated the process, and the results were identical. Biphasic neuron positive, NeuroD positive, with cell morphology exactly as previously seen. Manstein took the two sets of results to Yang Ping’s office.

Yang Ping finished looking over the two reports, placed them on the desk, leaned against his chair, and stared at the ceiling.

"Professor, did you anticipate this?"

"Guessed it when the tissue section results from M21 came out. Now we’ve found evidence, it holds true in humans too."

Manstein sat down, looking at Yang Ping. What could he say? His theory was correct, his prediction was correct, every insistence he made was correct. But Manstein knew Yang Ping would never say, "I was right." Yang Ping always focuses on what to do next, not on proving past success.

"Professor, we now have three layers of evidence. The first layer, M7’s primate acute injury model. The second layer, M8’s primate chronic injury model. The third layer, M21’s non-target intervention accidental recovery. Now with Clara’s cerebrospinal fluid, the fourth layer—human clinical evidence. Four layers of evidence, from rodents to primates to humans, from acute to chronic to non-targeted. This theory is no longer a theory; it’s a fact."

Yang Ping took out the heavily folded white paper from his pocket; it was his original draft proposing the three-dimensional spatial orientation gene theory. The paper’s creases were about to tear. He spread it on the desk, looking at the dense writing, the arrows and question marks, and the sentences that were crossed out and rewritten.

"Professor, do you still keep this?"

"I do. Sometimes it’s helpful to look back at my initial thoughts and remind myself not to deviate; some things have never changed."

"What hasn’t changed?"

"The core of the entire theory lies in two focal points—in bringing the desired cells to the desired location! The three-dimensional spatial orientation gene theory explains one aspect, while stem cell theory explains another; these two theories should fundamentally be unified. Now, I’m wondering if we should seek an even deeper unified theory."

Manstein looked at Yang Ping, feeling immensely shocked, his heartbeat uncontrollably accelerating, knowing the profound significance of this unified theory.

"You’re saying that stem cells and three-dimensional spatial orientation genes are essentially a unified theory, just like quantum mechanics and classical mechanics can be unified?"

"Yes, from a fertilized egg onwards, the body repeats this task, ensuring desired cells appear in desired locations, which cannot be lacking. Regulation of cell differentiation and spatial orientation is essentially a mechanism, I surmise."

"It’s so thrilling, Professor!"

"It certainly is a bit!"