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When Chris learned that Ivan lost his daughter, he felt a strong grief.
But he wasn't able to go help him or something, as he was in the middle of a mission.
But when she died was… the turning point for Ivan.
He changed.
It could be said that the old Ivan died with his daughter and his wife.
And what emerged afterwards was a man born from suffering and sorrow, an insane persona that wasn't really Ivan as Chris knew him.
After the death of his daughter, Ivan used his studies and investigations as a way to cope.
He put his mind into only that and nothing else.
Stealing secret information from the Organization and more, he did it all for his goals.
The goals to make a virus with the power to make humans invincible.
Virus had a particularly interesting ability, the way they caused diseases was by parasitizing a cell and infecting them, changing their DNA, and duplicating themselves within it.
This way, he wanted to modify a Virus already existing which was originally created for that but was deemed a failure because it caused incompatible hosts to turn into insane zombie-like monsters instead, causing rotting of the body and in some cases, cancerous mutations.
But Ivan wanted to use it and improve upon it with all the technology and knowledge he had as a genius… and he did everything he could, spending years isolated.
He had requested his daughter's corpse, and he froze her in a massive refrigerator back home, where he kept her.
Although she had already died, he couldn't possibly let her rot away.
There was a way… he had to find a way.
As the years went by, Chris never learned anything more about Ivan, as if he had simply gone out of existence.
Where could his friend be from all places?
He looked everywhere, but never found him.
What could have happened to Ivan?
He never got to know the truth…
He always wondered what could have happened to his good friend, and always sought for him everywhere he could, but Ivan was simply nowhere to be seen.
At some point, in New York, there was a break of a strange virus… and that's where everything began.
Over time, a strange secret organization was known to have spread a Virus in several areas of the world, testing it, and seeing if it worked on many people, seeking those with enough genes capable of resisting it, this caused enormous catastrophes as this virus was used as a bioweapon to terrorize countless innocents.
Chris never knew who was behind it until very late, when in a raid over one of the secret hideout where his organization dwelled, he found his good old friend, completely changed now.
"Ivan… is that you, Ivan?!" asked Chris back then.
"Long time no see, my good friend, Chris." Said Ivan.
His way of speech was different, his demeanor was different, everything on him… was not like he used to be.
But his face was the same.
"Ivan Wesker, you're accused of the indirect murder of millions! Surrender or we are allowed to shoot you down!" roared one of the soldiers.
"No… This can't be…" muttered Chris.
"Hmph. Vermin, do you think you can even amount to anything in the great scheme of things? I have already surpassed a normal human." Said Ivan back then, as he showed Chris what sort of monster he had turned himself…
After this initial fight where Chris doubted at the end and couldn't shoot down his old friend, a game of cat and mouse where Chris and the Organization constantly chased down Ivan everywhere began.
Chris, using the many clues, quickly realized that Ivan had done it all for his daughter.
He wanted a way to "revive" her, somehow, he had kept her corpse frozen in a hidden facility, but no matter how much he tried, the virus didn't do it, it wasn't going to be able to do what he wanted.
However, at some point, Ivan was registered to have infiltered in Africa, and the Organization once more chased him down.
This is where things changed, as Ivan found this new entity, the Mold.
The Mold was a being not from this world, a strange being that he had little knowledge of, but that was able to infect hosts and make them near immortal.
This was… it!
Ivan fought against Chris forces and once more managed to escape with the Mold. At the end, he was able to do the unthinkable, and managed to "revive" Miranda using the Mold.
But… was that girl really Miranda?
She didn't remembered her father, nor she remembered anyone else, she was like a newborn.
Her brain cancer was healed after her revival by the mold, but her memories and everything else… was gone.
Ivan tried his hardest to keep her alive, as she always showed complications, her body had been dead for way too long, and the Mold was unstable as an entity as well, he was forced to treat his daughter like a test subject and keep her alive through the usage of many types of vaccines and more, always keeping her entire body with needles.
Because he had lost his humanity, he was not capable of showing his emotions, and he was rough with her, inflicting fear on her, his obsession with Miranda only grew larger over time, as he didn't wanted her to go away from him, her attempts at escaping were forcefully stopped by him, as she was once more moved back to her laboratory where she was kept alive…
However, at some point, when she grew strong enough, the Mold helped her escape, and utter Chaos was unfolded, the world got to know about the Mold, and dozens of cases of people being turned into Mold Monsters, Miranda was ultimately tracked down, and after fighting Ivan countless times, who was trying to stop Chris from catching the girl, Chris finally managed to find her, and although he doubted, he and his men ended putting her down for good…
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